The cultural activities of Saint Roch's School are of two different types.

a. The School organizes:

• Cycles of lectures on historical and artistic topics,  study conferences and cultural shows organised by the School as well as other institutions;
• Exibitions about works and objects of art of its artistic heritage, which are exibited during particular restaurations and occasions.

b. The School edits and publishes:

• A collection of books entitled "Quaderni of the Scuola Grande Arciconfraternita di San Rocco", now in its tenth issue;
• A News Bulletin, which is published twice a year, in May and December;
• A series of books entitled "Quaderni delle Scuole di Venezia", with the other School located in Venice, now in its fifth issue;
• Other publications which directly relate to the School are also sponsored, such as art books (especially on Tintoretto), sculptures and ceramics catalogues, historical studies, etc. 

The School is part of the “Venezia Laboratorio Cultura” of the Comune of Venice.